Is there a difference between soy sauce brands? Absolutely. The main difference to watch out for is the salt content. Considering soy sauce is widely used in Korean cooking, the "right" or "wrong" soy sauce can easily make or break your recipe. Unless you are using a good Korean brand soy sauce, use caution when picking up just any soy sauce from the supermarket. Generally speaking if your selection is limited to only those offered in American supermarkets, the low-sodium versions will be your best choice.